Regulome Summit: Schedule

Time Session Details
8:00 AM Registration Check in, badges, coffee, buffet breakfast, veg, GF, DF options
9:00 AM Welcome, plenary Opening remarks
10:00 AM Northwest Sarcoma Foundation Patient and clinical perspectives
11:00 AM Session 1, AI and ML Session Chair: William E Fondrie, PhD
12:00 PM Lunch Hot buffet lunch, veg, GF, DF options
1:30 PM Keynote - Prof Steven Henikoff Title: “Histone overexpression in cancer”
2:00 PM Session 2, Epigenetics Session Chair: Lindsay K Pino, PhD
3:00 PM Session 3, Drugging the Undruggable Session Chair: Gaelle Mercenne, PhD
4:00 PM Posters and happy hour Reception, appetizers, snacks, dessert, beer, wine, NA drinks

Catering

  • Breakfast and lunch are buffet style, serve yourself.
  • Vegetarian, gluten free, and dairy free options at both meals.
  • Reception includes appetizers, snacks, and a dessert option.
  • Drinks at reception, beer, wine, and non-alcoholic beverages, sodas and water with lemon.

Welcome, plenary

Short orientation. Context and logistics.

Northwest Sarcoma Foundation

This session will highlight the challenges and opportunities of developing therapies for chordoma, a rare bone cancer driven by the transcription factor TBXT. Featuring the president of the Northwest Sarcoma Foundation, Dr. Schaub, and two patients with chordoma, the discussion will bridge advocacy, lived experience, and scientific innovation, underscoring the importance of collaboration in advancing treatments for rare cancers. (learn more)

Speakers

  • Gaelle Mercenne, PhD

  • Jo McNeal

Session 1, AI and ML

Models matter only if they predict and explain biology well enough to change decisions. We discuss the challenges and opportunities in building and testing models for actionable biology insights, then connect those models to industry applications such as screening design and target triage.

Session Chair: William E Fondrie, PhD

Speakers and talks

  • Ken Horenstein

  • Avery Sonnenberg, PhD

Keynote

Frontier view on nuclear proteomics and translational impact.

Speaker: TBA

Abstract

Abstract TBA

Session 2, Epigenetics

The nucleus is a complex biomolecular environment where proteins, DNA, and RNA interact in ways that challenge conventional measurement. We compare our favorite—and least favorite—technologies for studying the regulome, where improvement is most needed, and which questions better tools could answer.

Session Chair: Lindsay K Pino, PhD

Speakers and talks

  • Gregory Block, PhD

  • Thelma M. Escobar, PhD

  • Ben Blue, PhD

  • Sudarshan Pinglay, PhD

Session 3, Drugging the Undruggable

This panel will bring together scientists and industry leaders, to discuss emerging strategies for targeting historically “undruggable” proteins such as transcription factors and chromatin regulators. Panelists will share perspectives on scientific breakthroughs, challenges in drug discovery, and the impact these advances could have on patients with cancers like chordoma, where the TBXT driver has long resisted therapeutic intervention.

Session Chair: Gaelle Mercenne, PhD

Speakers and talks

  • Gavin Hirst, PhD

  • Jerry Shipps, PhD

  • Tara Arvedson, PhD

  • Devin Schweppe, PhD

Posters and happy hour

Reception and networking.

Poster details
  • Setup time and location
  • Poster size and format
  • Presenter timing
  • Best poster note if applicable
Food and beverage at reception
  • Appetizers, snacks, dessert
  • Beer, wine, sparkling, red and white
  • Non-alcoholic options, sodas and water with lemon